Systems operators are responsible for deploying and maintaining a DataSHIELD server. Currently there are two options, Armadillo and Opal. Armadillo is built and maintained by Molgenis, and was designed as a light-weight server specifically to implement DataSHIELD analysis. Opal is built and maintained by Obiba, and is a server which supports DataSHIELD analysis and also contains many additional features.
Both solutions share core functionality, and can be administered either using a user interface or R. However, the steps involved will be different.
Both solutions have documents explaining the installation process:
Armadillo documentation
Opal documentation