Systems operators are responsible for deploying and maintaining a DataSHIELD server. Currently there are two options, Opal and Armadillo. Opal (first released 2011) is built and maintained by Obiba, and is a data management server which supports DataSHIELD analysis and also contains many additional features. Armadillo (first released 2021) is built and maintained by Molgenis, and was designed as a light-weight server specifically to implement DataSHIELD analysis.
Both solutions share core functionality, and can be administered either using a user interface or R. However, the steps involved will be different.
Both solutions have documents explaining the installation process:
Opal documentation
Armadillo documentation
A list of deployment documentation from various consortia using DataSHIELD is also available.